World Journal of Epidemiology and Cancer Prevention Volume No 6

Original Article Open Access

A paired group study to evaluate the perinatal transmission of Human papilloma virus in high prevalence area

Raunak R Mankodi, Royana Singh, Rashmi Jaiswal, Ruhi Dixit, Baldev D Bhatia, Anuradha Khanna and Manoj Pandey
World Journal of Epidemiology and Cancer Prevention 2012, 1:2

Abstract

Introduction

In areas of high prevalence of HPV in the population, it may be transmitted to the oral cavity of the child from the mother.

Patients and methods

We collected endocervical swabs from 84 mother and oral swabs from the neonate. DNA was extracted, amplified and checked for HPV-16 and HPV-18 DNA.

Results

Of the 84 women child pair analysed, 60% of the women were found to have HPV DNA in endocervical smear, while buccal smears from 2% of the neonates were positive.

Conclusions

The results suggest a low frequency of the perinatal transmission of HPV in this part of the world.




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