Doppler Ultrasound Evaluation of the Axilla in Clinically Node Negative Breast Cancer
Abhijit Das, Rahul Khanna, RN Meena, Ram C Shukla, Mohan Kumar and Seema Khanna
World Journal of Surgical Medical and Radiation Oncology 2012, 1:13
Aim and Objective: The study was conducted to evaluate the use of Doppler ultrasound in preoperative evaluation of clinically node negative axilla in patients with breast cancer and to correlate the findings with the tissue diagnosis obtained on subsequent sentinel lymph node biopsy or axillary dissection specimen.
Patients and Methods: 86 biopsy proven cases of breast cancer with clinically negative axilla were evaluated using 7.5 MHz high frequency ultrasound with Doppler. The L/S ratio, H/L ratio, flow pattern of lymph node, Resistivity Index (RI) and Pulsatility Index (PI) were recorded.
Results: On the basis of the Doppler ultrasound findings it is possible to identify the subset of patients at high-risk of harboring nodal metastasis and these patients can be offered axillary nodal dissection upfront.
Conclusions: Patients who have an equivocal or indeterminate or negative axilla on Doppler ultrasound should be advised to undergo sentinel lymph node biopsy prior to decisions regarding further management of the axilla.