World Journal of Surgical Medical and Radiation Oncology Volume No 6

Case Report Open Access

Hyperinsulinemic Hypoglycemia due to Diffuse Nesidioblastosis in Adults

Nan Xiang, Chi-hua Fang, Ying-fang Fan and Jian Yang
World Journal of Surgical Medical and Radiation Oncology 2013, 2:5

Abstract

Background

Nesidioblastosis is a rare cause of adult-onset hyperinsulinemic hypoglycemia. We describe a 28-year-old lady who presented with sudden loss of consciousness. Hyperinsulinemic hypoglycemia was found.

Material and Methods

Preoperative imaging’s and intraoperative ultrasound failed to identifiy any pancreatic insulinoma. Selective intra-arterial calcium stimulation with venous sampling showed an elevated insulin level within the distal splenic vein. Open distal pancreatectomy was performed.

Results

Histopathology confirmed nesidioblastosis.

Conclusions

Her recovery was uneventful.

Keywords

Hyperinsulinemic hypoglycemia; Adult nesidioblastosis; Distal pancreatectomy, insulinoma.




Download PDF    Full Text