World Journal of Surgical Research Volume No 6

Research Open Access

Comparative Study of Magnified Oral Examination and Various Staining Techniques for Detection of Oral Cavity Lesions

Shashi Prakash, Satendra Kumar, Gaurav Kulwal, Satyendra K Tiwary and Ajay K Khanna
World Journal of Surgical Research 2013, 2:5

Abstract

Background

Oral cancer is a frequently encountered entity which can occur even without any signs of dysplasia or carcinoma in situ. Hence histology is mandatory for diagnosis.

Material and Method

In a prospective study, a total of 40 patients in the age group of 30-70 years having oral lesions were included. We compared the results of biopsy after magnified oral examination and also by various staining technique with clinical examination alone and also with each other in 40 patients.

Results

Maximum number (19/35) of malignant cases were detected by direct oral microscopy followed by toluidine blue and double chromoscopy (15/35) each. By clinical examination only 10 malignant cases were detected out of 35 cases. Acetowhite staining and lugol’s iodine detects only 9 & 12 malignant cases.

Conclusion

We concluded on the basis of distribution that direct oral microscopy followed by toluidine blue and double chromoscopy were better diagnostic modality than clinical examination.




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