World Journal of Pathology Volume No 6

Case Report Open Access

Gaint Cell Tumor of Tendon Sheath Involving Second Metacarpal Bone: –A Rare Case Report

Nagarekha Kulkarni and Phaniraj G
World Journal of Pathology 2013, 2:15



Giant cell tumor of tendon sheath (GCTTS) is a benign slow growing tumor with a high incidence of recurrence. Intraosseous metacarpal involvement of GCTTS is an uncommon manifestation of this tumor, but it is well known because of its potentially aggressive local growth. Only few cases are reported in the literature.

Case Report

A 22 years old female presented with pain and swelling over the left hand since 3 months. X-ray findings revealed soft tissue lesion over left second metacarpal. On the radial aspect there was a bony erosion of the second metacarpal involving the cortex of the metacarpal. Tumor along with partial excision of left second metacarpal was removed and sent for histopathological examination. Microscopically an admixture of polygonal and spindle shaped mononuclear cells, xanthoma cells, multinucleated gaint cells in a collagenous, variably hyalinised stroma was seen. The histopathological diagnosis of gaint cell tumor of tendon sheath was made.


To conclude this entity has to be kept in mind when there is a swelling in the metacarpal area.

Key Words

intraosseous, synovial, fibrous histiocytoma

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